Home Chemistry Organometallic Reagents Organoborons (E)-4,4,5,5-Tetramethyl-2-Styryl-1,3,2-Dioxaborolane
Suzuki-Miyaura Cross-Coupling: (E)-4,4,5,5-tetramethyl-2-styryl-1,3,2-dioxaborolane can be used as a boron source in Suzuki-Miyaura cross-coupling reactions. In this reaction, it can react with aryl or vinyl halides under the influence of a palladium catalyst to form new carbon-carbon bonds. This is a valuable reaction for synthesizing biaryl compounds and other organic molecules.
Negishi Cross-Coupling: This boron compound can also participate in Negishi cross-coupling reactions. In this reaction, it reacts with organozinc reagents, typically formed in situ from organohalides and zinc reagents, under the influence of a palladium catalyst. It is another method for forming new carbon-carbon bonds.
Buchwald-Hartwig Amination: (E)-4,4,5,5-tetramethyl-2-styryl-1,3,2-dioxaborolane can be used in Buchwald-Hartwig amination reactions to introduce an amino group into the molecule. This reaction typically requires a suitable amine source and a palladium catalyst.
Sonogashira Cross-Coupling: In a Sonogashira cross-coupling reaction, this boron compound can be used to form carbon-carbon bonds between the boron atom and an alkynyl or aryl halide. This reaction is useful for synthesizing alkynes and functionalized aryl compounds.
Stille Cross-Coupling: Stille cross-coupling reactions can be carried out using (E)-4,4,5,5-tetramethyl-2-styryl-1,3,2-dioxaborolane and organotin reagents, typically in the presence of a palladium catalyst. This reaction allows the formation of carbon-carbon bonds.
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(E)-4-(2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)vinyl)benzonitrile
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(E)-2-(4-Bromostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(3,5-Dimethoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(3,5-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-4,4,5,5-Tetramethyl-2-(3-(trifluoromethyl)styryl)-1,3,2-dioxaborolane
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(E)-2-(4-Methoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(4-Chlorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-4,4,5,5-Tetramethyl-2-(4-methylstyryl)-1,3,2-dioxaborolane
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2-(2-Fluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Trans-2-Phenylvinylboronic acid pinacol ester
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(E)-2-(4-Butylstyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(2,4-Difluorostyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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(E)-2-(3-Methoxystyryl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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