Home Chemistry Heterocyclic Building Blocks Indazoles 4-Methyl-1H-Indazole
Substitution Reactions: The methyl group or the nitrogen atom in the indazole ring can undergo various substitution reactions, such as nucleophilic substitution or electrophilic substitution, leading to the formation of substituted indazoles.
Alkylation: The nitrogen atom in the indazole ring can be alkylated by reaction with alkyl halides or sulfonates.
Acylation: The nitrogen atom in the indazole ring can undergo acylation reactions to form N-acyl derivatives.
Reduction: The nitro group can be reduced to the corresponding amine using reducing agents such as hydrogen gas over a metal catalyst or stannous chloride.
Oxidation: The methyl group or other substituents can be oxidized to form corresponding alcohols, aldehydes, or carboxylic acids under appropriate conditions.
Ring-closure Reactions: It can undergo ring-closure reactions to form cyclic compounds or fused-ring systems under suitable conditions.
Condensation Reactions: It can participate in condensation reactions with carbonyl compounds or other nucleophiles to form cyclic compounds or larger molecules.
Halogenation: The indazole ring can undergo halogenation reactions with halogenating agents such as bromine or chlorine.
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(4-Methyl-1H-indazol-5-yl)boronic acid
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7-Iodo-6-methoxy-4-methyl-1H-indazole
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