Home Chemistry Organic Building Blocks Chlorides 2-Chloro-1,3-Difluorobenzene
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —Cl,—F).
Grignard Reaction: Chlorobenzene can react with magnesium metal to form phenylmagnesium chloride, which can then react with various electrophiles to introduce new functional groups onto the aromatic ring.
Electrophilic Aromatic Substitution (EAS): Fluorobenzene can undergo typical electrophilic aromatic substitution reactions, similar to benzene. The fluorine atom, being electron-withdrawing, can influence the reactivity of the benzene ring. Common EAS reactions include nitration, halogenation, sulfonation, and Friedel-Crafts reactions.
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(4-Chloro-3,5-difluorophenyl)boronic acid
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2-(3-Chloro-2,4-difluorophenyl)acetonitrile
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3-Chloro-2,4,5-trifluorobenzoyl chloride
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Ethyl 3-(3-chloro-2,4,5-trifluorophenyl)-3-oxopropanoate
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(3-Chloro-2,4-difluorophenyl)boronic acid
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