C/EBP (CCAAT/Enhancer Binding Protein) is a group of transcription factors that regulate gene expression, including family members such as C/EBPα, β, γ. These proteins contain a basic leucine zipper domain and are primarily localized in the nucleus. C/EBP regulates signaling pathways involved in cell differentiation, metabolism, and immune responses. They activate or inhibit the expression of target genes by binding to specific DNA sequences. Specific gene expression and mutations play significant roles in various physiological and pathological processes, such as in cancer and inflammatory responses.