Home Chemistry Organic Building Blocks Fluorinated Building Blocks 2,4-Difluorobenzonitrile
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —F,—C≡N).
Cross-Coupling Reactions: Fluorobenzene can be utilized in cross-coupling reactions, such as Suzuki-Miyaura, Negishi, and Stille reactions. These reactions involve coupling a halogenated aromatic compound with an organometallic reagent, resulting in the formation of new carbon-carbon bonds.
Cyanation and Cyanation Reactions: The cyano group in benzonitrile can serve as a nucleophile in various reactions, leading to the introduction of cyano groups onto other molecules.
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