Home Chemistry Heterocyclic Building Blocks Pyridines 2-Iodo-6-Methylpyridine
Substitution Reactions: Being an alkyl halide, 2-iodo-6-methylpyridine can undergo substitution reactions, where the iodine atom is replaced by another nucleophile. This could include reactions such as nucleophilic substitution, where a nucleophile replaces the iodine, or metal-halogen exchange reactions.
Metalation Reactions: The pyridine ring in 2-iodo-6-methylpyridine can undergo metalation reactions, where a metal (often a strong base such as butyl lithium) abstracts a proton from the methyl group or the pyridine ring, leading to the formation of a metal-carbon bond.
Cross-Coupling Reactions: 2-Iodo-6-methylpyridine can participate in cross-coupling reactions, such as Suzuki, Heck, or Sonogashira reactions, where it reacts with suitable coupling partners in the presence of appropriate catalysts to form biaryl compounds or heterocyclic compounds.
Redox Reactions: It can undergo various redox reactions where the iodine may be involved in oxidation or reduction processes, depending on the reaction conditions and the presence of suitable reagents.
Functional Group Transformations: The methyl group in 2-iodo-6-methylpyridine can undergo various transformations, such as oxidation to a carboxylic acid or reduction to a methyl group. The pyridine ring can also undergo various functional group transformations, such as oxidation to a pyridine N-oxide or reduction to a piperidine.
Arylation Reactions: The pyridine ring can undergo arylation reactions where an aryl group is introduced onto the ring. This can occur through transition metal-catalyzed reactions or through other methods such as direct arylation.
Halogenation Reactions: The pyridine ring can undergo halogenation reactions, where additional halogen atoms are introduced onto the ring. This can occur through electrophilic aromatic substitution reactions.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Heterocyclic related+−
Formula Weight+−
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :