FOXM1 (Forkhead box protein M1) is a member of the Forkhead box (Fox) gene family, characterized by a specific DNA-binding domain that recognizes and binds to specific DNA sequences. FOXM1 is primarily located in the nucleus and is a key regulator of the cell cycle, particularly involved in DNA damage repair and cell division. It activates genes associated with the cell cycle through various signaling pathways. The expression of FOXM1 is abnormally high in rapidly proliferating cells and tissues such as cancers, and its mutations or overexpression are closely associated with the development of various cancers.