Home Chemistry Heterocyclic Building Blocks Pyrrolidines 3-Phenoxypyrrolidine
Nucleophilic Substitution: The pyrrolidine nitrogen atom is nucleophilic, and it can undergo substitution reactions with electrophiles. For example, it can react with alkyl halides or acyl halides to form N-substituted pyrrolidines.
Acylation: The phenoxy group is a potential site for acylation reactions. You can react 3-phenoxypyrrolidine with acyl chlorides or anhydrides to form amides or esters, depending on the reaction conditions.
Reduction: The carbonyl group in the pyrrolidine ring can be reduced to an alcohol using reducing agents like sodium borohydride (NaBH4) or lithium aluminum hydride (LiAlH4).
Oxidation: The phenolic group can be oxidized to a quinone or other oxidized forms using oxidizing agents like potassium permanganate (KMnO4) or hydrogen peroxide (H2O2).
Ring-Opening Reactions: Under certain conditions, pyrrolidine rings can undergo ring-opening reactions, particularly when subjected to strong acids or bases. This can lead to the formation of open-chain compounds.
Grignard Reaction: 3-Phenoxypyrrolidine can react with a Grignard reagent (alkyl or aryl magnesium halide) to form a substituted pyrrolidine derivative.
Cross-Coupling Reactions: The phenolic group can participate in cross-coupling reactions with aryl or alkyl halides to form biaryl or alkyl-aryl compounds.
Polymerization: In the presence of suitable initiators or catalysts, 3-phenoxypyrrolidine can participate in polymerization reactions, leading to the formation of polymers.
Framework+−
By Key Group+−
By Parent Nucleus+−
By Functional Group+−
Formula Weight+−
click to sign in and save
3-(4-Fluorophenoxy)pyrrolidine hydrochloride
click to sign in and save
Methyl 3-(pyrrolidin-3-yloxy)benzoate hydrochloride
* Country/Region
* Quantity Required :
* Cat. No.:
* CAS No :
* Product Name :
* Additional Information :