Home Chemistry Organic Building Blocks Carboxylic Acids 2-(O-Tolyl)Acetic Acid
These compounds have the same murcko framework: benzene,and at least 2 kinds of functional groups( —CH2COOH,—CH3).
Decarboxylation: Under certain conditions, 2-phenylacetic acid can undergo decarboxylation, which results in the loss of carbon dioxide and formation of a substituted 【benzene compound|https://www.ambeed.com/benzene-compounds.html】. Reaction: 2-Phenylacetic acid → Substituted Benzene Compound + Carbon Dioxide
Alkylation: Similar to acylation, toluene can also undergo Friedel-Crafts alkylation reactions, where an alkyl group is introduced onto the benzene ring. Alkylation reactions also require a Lewis acid catalyst.
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