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Chemical Structure| 32364-72-0 Chemical Structure| 32364-72-0

Structure of 32364-72-0

Chemical Structure| 32364-72-0

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Product Details of [ 32364-72-0 ]

CAS No. :32364-72-0
Formula : C10H6O2S2
M.W : 222.28
SMILES Code : O=CC1=CC=C(C2=CC=C(C=O)S2)S1
MDL No. :MFCD00839981
InChI Key :RXAXZMANGDHIJX-UHFFFAOYSA-N
Pubchem ID :2063643

Safety of [ 32364-72-0 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H315-H319
Precautionary Statements:P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

Application In Synthesis of [ 32364-72-0 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 32364-72-0 ]

[ 32364-72-0 ] Synthesis Path-Downstream   1~4

  • 1
  • [ 4805-22-5 ]
  • [ 33513-42-7 ]
  • [ 32364-72-0 ]
YieldReaction ConditionsOperation in experiment
76% 5, 5'-diformyl-2, 2'-bithiophene (35): To a solution of 5,5'-dibromo- 2,2'-bithiophene (2.00 g, 6.17 mmol, Aldrich Co. ) in anhydrous THF (30 mL) was added dropwise n-butyllithium (5.43 mL, 13.6 mmol, 2.5 M in hexanes, Aldrich Co. ) AT-78C under argon. The mixture was stirred 30 min. AT-78C, warmed to room temperature and stirred for an additional 90 minutes. Anhydrous dimethylformamide (1.43 mL, 18.5 mmol, Aldrich Co. ) was added dropwise and the solution was stirred at room temperature for another 2 h. An aqueous HCI solution (1 M, 10 mL) was slowly added followed by the addition of acetone (50 mL). The resulting mixture was poured into 150 mL of hexanes at 0C and the brown precipitate was filtered, washed with hexanes and dried under vacuum for 24 h to provide 1.05 g of the title product as a orange-brown solid. M. P.: 213-214C (Yield : 76 %). 1H NMR (400 MHz, DMSO-d6, ppm): 9.89 (s, 2H); 8.00 (d, 2H, J = 4.0 Hz); 7.73 (d, 2H, J = 4.0 Hz). 13C NMR (100 MHz, DMSO-D6, ppm): 185.00 ; 144.14 ; 144.03 ; 139.60 ; 128. 57.
  • 2
  • [ 1455-20-5 ]
  • [ 4701-17-1 ]
  • [ 32364-72-0 ]
  • [ 1062177-05-2 ]
  • 3
  • [ 4701-17-1 ]
  • [ 17626-75-4 ]
  • [ 32364-72-0 ]
  • 5-(2-propylthiazol-5-yl)thiophene-2-carbaldehyde [ No CAS ]
  • 4
  • [ 4394-85-8 ]
  • [ 4805-22-5 ]
  • [ 32364-72-0 ]
YieldReaction ConditionsOperation in experiment
69.4% TT-Br (1.00 g, 3.08 mmol) was dissolved in distilled tetrahydrofuran (THF, 30 mL). With stirring, a solution of 1.6 M n-butyllithium in hexane (3.64 mL) was added dropwise at -78C, and the reaction mixture was stirred for 2 h. After stirring, 4-formylmorpholine (0.820 g, 7.09 mmol) was added dropwise to the reaction mixture, stirred for another 1 h, and warmed to rt. After stirring at rt for 2 h, the mixture was poured into methanol (150 mL) and filtered to give a yellow solid product. Yield: 0.470 g (69.4%). 1H NMR (400 MHz, CDCl3): δ (ppm) 9.92 (s, 2H), 7.73 (d, J = 4.0 Hz, 2H), 7.43 (d, J = 3.9 Hz, 2H).
 

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