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Chemical Structure| 859169-88-3 Chemical Structure| 859169-88-3

Structure of 859169-88-3

Chemical Structure| 859169-88-3

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Product Details of [ 859169-88-3 ]

CAS No. :859169-88-3
Formula : C16H23BO4
M.W : 290.16
SMILES Code : O=C(O)CCCC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1

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Application In Synthesis of [ 859169-88-3 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 859169-88-3 ]

[ 859169-88-3 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 27913-58-2 ]
  • [ 73183-34-3 ]
  • [ 859169-88-3 ]
YieldReaction ConditionsOperation in experiment
95% With potassium acetate;(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In dimethyl sulfoxide; at 100℃; for 18h; 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]butanoic acid: 4-(4-Iodophenyl)butanoic acid (40.0 mg, 0.130 mmol), 4,4,5,5-tetramethyl-2-(4,4,5,5-tetramethyl(1,3,2-dioxaborolan-2-yl))-1,3,2-dioxaborolane (bis(pinocolato)diboron) (33.3 mg, 0.150 mmol), potassium acetate (54.1 mg, 0.550 mmol) and 1,1'-bis(diphenylphosphino)ferrocenedichloropalladium (5.60 mg, 5 mol %) in dimethylsulphoxide (1.50 mL) was heated at 100 C. for 18 h. The reaction mixture was concentrated in vacuo to leave a dark oil. The residue was diluted with EtOAc, filtered and the filtrate was concentrated in vacuo to leave the crude acid (38.0 mg, 95%). ESMS m/e: 291.2 (M-H)-.
 

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