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Chemical Structure| 35511-14-9 Chemical Structure| 35511-14-9

Structure of 35511-14-9

Chemical Structure| 35511-14-9

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Product Details of [ 35511-14-9 ]

CAS No. :35511-14-9
Formula : C10H9NO5S
M.W : 255.25
SMILES Code : O=C(C1=C(O)C2=CC=CC=C2S(N1)(=O)=O)OC
MDL No. :MFCD00071753

Safety of [ 35511-14-9 ]

GHS Pictogram:
Signal Word:Warning
Hazard Statements:H302-H315-H319-H335
Precautionary Statements:P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501

Application In Synthesis of [ 35511-14-9 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 35511-14-9 ]

[ 35511-14-9 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 35511-14-9 ]
  • [ 33332-28-4 ]
  • [ 91286-70-3 ]
YieldReaction ConditionsOperation in experiment
In 5,5-dimethyl-1,3-cyclohexadiene; EXAMPLE 7 N-(6-Chloro-pyrazin-2-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide A mixture of 5.1 g (20 mmols) of methyl 4-hydroxy-2H-1,2-benzothiazine-3-carboxylate-1,1-dioxide, 3.0 g (23 mmols) of <strong>[33332-28-4]2-amino-6-chloropyrazine</strong> and 400 ml of xylene was refluxed for 12 hours in a nitrogen atmosphere. The methanol formed by the reaction was removed with the aid of a 4 A molecular sieve arranged in a Soxhlet attachment. After cooling, the reaction mixture was concentrated by evaporation, and the residue was purified by chromatography on a silicagel column, yielding 2.3 g (33percent of theory) of N-(6-chloro-pyrazin-2-yl)-4-hydroxy-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide. Melting point: 234°-235° C. (from ethanol). C13 H9 ClN4 O4 S (352.76): Calc.: C--44.26percent; H--2.57percent; N--15.88percent; Cl--10.05percent; S--9.09percent. Found: C--44.02percent; H--2.65percent; N--15.92percent; Cl--10.10percent; S--9.24percent.
 

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