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Chemical Structure| 797035-61-1 Chemical Structure| 797035-61-1

Structure of 797035-61-1

Chemical Structure| 797035-61-1

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Product Details of [ 797035-61-1 ]

CAS No. :797035-61-1
Formula : C22H16Br2
M.W : 440.17
SMILES Code : CC1=CC(Br)=C2C=CC=CC2=C1C3=C4C=CC=CC4=C(Br)C=C3C

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Application In Synthesis of [ 797035-61-1 ]

* All experimental methods are cited from the reference, please refer to the original source for details. We do not guarantee the accuracy of the content in the reference.

  • Downstream synthetic route of [ 797035-61-1 ]

[ 797035-61-1 ] Synthesis Path-Downstream   1~1

  • 1
  • [ 870774-25-7 ]
  • [ 797035-61-1 ]
  • [ 1359730-64-5 ]
YieldReaction ConditionsOperation in experiment
38% Synthesis Example 1 This example illustrates the preparation of compound A1 .To a 500 ml_ round bottle flask were added 4,4'-dibromo-2,2'-dimethyl-1 ,1 '- binaphthyl (4.40 g, 10 mmol), 4-(naphthalen-1 -yl)phenylboronic acid (5.21 g, mmol), sodium carbonate (2 M, 30 ml_, 60 mmol), toluene (120 ml_) and Aliquat 336 (0.5 g). The mixture was system was stirred under nitrogen for 20 min. After which Tetrakis(triphenylphosphine) (462 mg, 0.4 mmol) was added and the mixture was stirred under nitrogen for another 15 min. The reaction was then heated in an oil bath at 95 C for 18 hour. After cooling, the mixture was filtered through a Celite pad to remove the insoluble materials. The solution was washed with diluted HCI (10%, 80 ml_), water (80 ml_) and saturated brine (50 ml_). The solvent was removed by rotary evaporation. The crude product was passed through a Silica gel column eluted with toluene. The product containing fractions were combined and the solvent was removed by rotary evaporation.Recrystallization from methylene chloride and acetonitrile gave the product as a white crystalline material. Yield, 2.6 g (38%). NMR spectra was consistent with the structure.
 

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